Gold Nanoparticles Inhibit Extravasation of Canine Osteosarcoma Cells in the Ex Ovo Chicken Embryo Chorioallantoic Membrane Model.

Inhibition of Cancer Cells Extravasation by Au-GSH NPs A twenty-four-hour cell co-culture with Au-GSH NPs, prior to iv injection, resulted in the inhibition of extravasation efficiency, statistically significant for OSCA-8 ( p -value ≤ 0.05) and highly significant for OSCA-32 ( p -value ≤ 0.01), through the decrease in extravasation rate of Au-GSH NPs-treated cells in comparison to untreated cells ( Figure 7 ).

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