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Editorial: Nutritional interventions on age-related neurodegenerative diseases.

Front Aging Neurosci · 2023 · PMC10299919 · PMID 37388186

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a decreasing trendno p-value reported
detected the levels of β-carboline alkaloids (βCBs), such as harmine, in plasma and tissues of pup rats, aging rats, mice of different physiological states, and healthy volunteers using UPLC-MS/MS and found that the concentration of harmine showed a decreasing trend with advanced age.

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