Stage-Dependent Increase of Systemic Immune Activation and CCR5<sup>+</sup>CD4<sup>+</sup> T Cells in Filarial Driven Lymphedema in Ghana and Tanzania.

Pathogens · 2023 · PMC10301430 · PMID 37375499

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an increasing trendno p-value reported

While expecting to observe a similar trend in this study with a larger cohort of LE individuals, we instead observed an increase only in the CD4 + CCR5 + T cells and an increasing trend for CD8 + CCR5 + T cells associated with an increasing LE stage in the Ghanaian cohort and with minute differences seen between the LE stage groups in the Tanzanian cohort.

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