Differential Activities of the Botanical Extract PBI-05204 and Oleandrin on Innate Immune Functions under Viral Challenge Versus Inflammatory Culture Conditions.

Molecules · 2023 · PMC10302683 · PMID 37375354

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.1000

boldest claim

The sentences

highly significantp < 0.01actually significant

The increased expression of CD69 on NK cells treated with PBI was highly significant at the three highest concentration, whereas for oleandrin this was seen for the two highest concentrations ( p < 0.01).

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a statistical trendp < 0.1so close (0.05 < p ≤ 0.1)

In addition, the test products also induced the production of the anti-inflammatory cytokine, interleukin-1 receptor antagonist (IL-1ra; Figure 3 E), with PBI inducing higher levels than oleandrin when administered at the 31.3 ng/mL concentration, reaching a statistical trend when compared to pure oleandrin ( p < 0.1).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.