Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas.

4 In IDH mutant gliomas in population 4, CpGs hypomethylated in NFKBIA deleted tumors ( Table S3 ) overlapped significantly with those hypomethylated in all NFKBIA deleted gliomas (73.7%) ( Figure S6 E and Table S3 ), and the association of those CpGs, whose presence denotes the G-CIMP-low subtype, remained highly significant ( Figure S7 A).

also in 132,142 other papers