Fusobacterium nucleatum-triggered purine metabolic reprogramming drives tumorigenesis in head and neck carcinoma.

Discov Oncol · 2023 · PMC10315358 · PMID 37393565

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an increasing trendno p-value reported

Moreover, its incidence shows an increasing trend and is estimated to increase 30% by 2030 [ 2 ].

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a decreasing trendno p-value reported

nucleatum could lead to a decreasing trend in purine degradation and thus a decreased uric acid level in HNSCC, which then facilitates tumor progression and results in poor patient outcomes.

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