Barely Significant
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The unique reactivity of 5,6-unsubstituted 1,4-dihydropyridine in the Huisgen 1,4-diploar cycloaddition and formal [2 + 2] cycloaddition.

Beilstein J Org Chem · 2023 · PMC10315888 · PMID 37404798

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might be significantno p-value reported
The potential application of this reaction in organic synthesis and medicinal chemistry might be significant.

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