What is the best reconstruction procedure after esophagectomy? A meta-analysis comparing posterior mediastinal and retrosternal approaches.

4.3 Mortality NCD revealed a decreasing trend in mortality rate for esophagectomy from 3.2% in 2011 to 1.5% in 2020, which is similar to the mortality rate for total gastrectomy. 10 Our meta‐analysis evaluated the effect of reconstruction routes on mortality in five RCTs including 125 posterior mediastinal and 129 retrosternal cases, 19 , 22 , 23 , 24 , 25 , 26 five case–control trials comprising 464 posterior mediastinal and 424 retrosternal cases, 18 , 19 , 30 , 33 , 35 , 36 and NCD analysis involving 3478 posterior mediastinal and 6308 retrosternal cases 7 (Figure 2C ).

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