Different definitions of feeding intolerance and their associations with outcomes of critically ill adults receiving enteral nutrition: a systematic review and meta-analysis.

J Intensive Care · 2023 · PMC10320932 · PMID 37408020

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marginally significantno p-value reported

3-day enteral feeding (EF) delivered percentage < 80% had a moderate hospital prevalence (38.23%, 95% CI 24.88–51.58) but a marginally significant association with all-cause hospital mortality (OR 1.90, 95% CI 1.03–3.50).

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marginal significanceno p-value reported

When FI has been defined as EF insufficiency with threshold indiscriminately or with EF percentage < 80% [cohorts with EF percentage < 20% and < 50% were completely covered by the same cohort [ 5 ] with EF percentage < 80%], it was associated with hospital mortality but with a marginal significance (OR 1.90, 95% CI 1.03–3.50; very low certainty evidence; Fig. 3 ) and showed no significant difference for other outcomes (Fig. 3 ).

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