TB preventive therapy preferences among children and adolescents.

20 Although shorter TPT regimens – isoniazid and rifampicin once daily for 3 months (3HR) – have been found efficacious with reportedly higher adherence rates compared to 6 months of daily isoniazid, 21 , 22 our findings suggest that the effect of shorter regimens on preferences is only likely to be significant if combined with fewer clinic visits.

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Caregivers mostly preferred formulations with two small pills, being less likely to choose alternatives with six small pills, two large pills or dissolvable formulations (all highly significant).

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