Repressive histone marks, such as histone H3 lysine 9 di- and tri-methylation (H3K9me2/me3), and H3K27me3 showed a decreasing trend during differentiation (from Day 0 to Day 2), which was inhibited by DFO treatment ( Supplementary Figure S3A ).
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Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity.
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