In our study, frequency distribution of WM-PVS grades according to different severity levels of ASD shows an increasing trend, with 80% “mild” ASD patients with less than 40 WM-PVS (WM-PVS grade 0–3) in a single MRI section and 53% “severe” ASD patients with more than 40 visible WM-PVS (WM-PVS grade 4).
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Brain perivascular spaces and autism: clinical and pathogenic implications from an innovative volumetric MRI study.
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