A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice.

NPJ Vaccines · 2023 · PMC10333387 · PMID 37429853

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highly significantno p-value reported

Mice injected with F 1 -CRM + alum + INI-4001 or with the triple adjuvant combination had a highly significant increase in serum fentanyl concentrations (Fig. 7c ), with an associated significant decrease in brain fentanyl concentrations (Fig. 7d ) when compared to F 1 -CRM only.

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