Quantitative assessment of the relevance of organic-anion-transporting-polypeptide 1B1 and 2B1 polymorphisms in fexofenadine pharmacokinetic variants via pharmacometrics.

J Pharm Anal · 2023 · PMC10334346 · PMID 37440913

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may be significantno p-value reported

This implied that the SLCO1B1 521T > C genetic polymorphisms increased plasma accumulation during multiple exposures to fexofenadine, and the degree may be significant in the CC genotype.

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