ACSS2-dependent histone acetylation improves cognition in mouse model of Alzheimer's disease.

Mol Neurodegener · 2023 · PMC10339567 · PMID 37438762

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may be significantno p-value reported

As ACSS2 acts as a key metabolic enzyme that regulates histone acetylation in neurons and affects the spatial memory in adult mice [ 20 ], it indicates that a reduction in ACSS2 may be significant in the context of AD.

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