Cyclophilin A Isomerisation of Septin 2 Mediates Abscission during Cytokinesis.

In contrast, a highly significant increase in midbody-flanking Sept2 ( p -value < 0.00001) and a corresponding decrease in Sept2 at the central midbody ( p -value < 0.00001) were detected relative to the Jurkat CypA+/+ cells ( Figure 1 E).

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