The generalized additive model (GAM) of oocyst shedding, using “smoothed time”, “isolate” and “pen” as fixed effects and “lamb” as a random variable explained only 14.1% of the deviance, with “smoothed time” being a highly significant variable ( P < 2.2 × 10 16 ), “isolate” also significant ( P = 0.0047), and “pen” not significant ( P = 0.41) ( Fig. 4 B).
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Differences in virulence and oocyst shedding profiles in lambs experimentally infected with different isolates of <i>Cryptosporidium parvum</i>.
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