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Evaluating the global, regional, and national impact of syphilis: results from the global burden of disease study 2019.

Sci Rep · 2023 · PMC10349077 · PMID 37452074

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a decreasing trendno p-value reported
The ASR of DALYs exhibited a decreasing trend from 1990 to 2019 (EAPC = − 1.01; 95% CI − 1.19 to − 0.84), with the highest rates observed in the younger age group (< 14 years old).

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an increasing trendno p-value reported
There was an increasing trend in the ASR of prevalence in high SDI regions (EAPC: 0.15, 95% CI 0.10–0.20) and high-middle SDI regions (EAPC: 0.12, 95% CI 0.01–0.23), whereas the incidence decreased in low SDI regions (EAPC: − 1.03, − 1.13 to − 0.93).

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.