Thus, an extremely significant number of regulators of RUNX2 gene expression have been identified, which is a promising therapeutic gene model in culture studies, as blocking or enhancing the activity of this gene and monitoring its expression level during the induction of osteogenic lines allows the identification of key switches of mesenchymal stem cell differentiation.
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Epigenetic regulation of bone remodeling and its role in the pathogenesis of primary osteoporosis.
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