The effect of type of the type of the inhibitor ( F = 12.77, p < 0.0001) and experimental condition ( F = 104.47, p < 0.0001) as well as of their interaction ( F = 17.88, p < 0.0001) were found to be highly significant.
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Pitstop-2 and its novel derivative RVD-127 disrupt global cell dynamics and nuclear pores integrity by direct interaction with small GTPases.
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