Association of Intima-Media Thickness Measured at the Common Carotid Artery With Incident Carotid Plaque: Individual Participant Data Meta-Analysis of 20 Prospective Studies.

When we used Cox regression based on the estimated time to plaque development, HRs were highly significant, although numerically lower than ORs, as expected when the rare disease assumption is not met (39% developed the outcome plaque).

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