a trend towards significancep = 0.10
Hyperthermia significantly increased the cytotoxicity of cisplatin (pooled analysis viability, 38.3% at 42 °C vs 62.6% at 37 °C, p = 0.02) and demonstrated a trend towards significance with MMC (50.6% at 42 °C and 73.3% at 37 °C, p = 0.10).