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Potential noninvasive biomarkers for the malignant transformation of oral leukoplakia: A systematic review and meta-analysis.

Cancer Med · 2023 · PMC10358244 · PMID 37199052

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an increasing trendno p-value reported
The results suggested that the concentration levels of IL‐6 and TNF‐α in the saliva of HCs and OL and OC patients exhibited an increasing trend, while no significant changes were observed in the other 5 salivary biomarkers, including IL‐1α, IL‐8, copper, zinc, and LDH (Figures S5–S14 ). 3.2.2.

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