Life course BMI trajectories from childhood to mid-adulthood are differentially associated with anxiety and depression outcomes in middle age.

Furthermore, the child average-increasing trajectory was more likely to experience irritability (OR = 1.86, 95%CI: 1.31, 2.64) and feelings of apprehension (OR = 1.67, 95%CI: 1.07, 2.59), whilst a positive trend was observed for feeling nervous/anxious (OR = 1.38, 95%CI: 0.96, 1.97, p = 0.08) and uncontrollable worrying (OR = 1.44, 95%CI: 0.98, 2.11, p = 0.06; Supplementary Table S 8 ) In sex-stratified models, males in the child high-decreasing trajectory (OR = 0.51 95%CI: 0.32, 0.83) were less likely to experience a greater severity of anxiety symptoms (Table 4 ).

also in 6,068 other papers