Febuxostat attenuates aluminum chloride-induced hepatorenal injury in rats with the impact of Nrf2, Crat, Car3, and MNK-mediated apoptosis.

Environ Sci Pollut Res Int · 2023 · PMC10359240 · PMID 37340161

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highly significantp < 0.05actually significant

Results Effect of febuxostat on serum hepatic markers in rats intoxicated with Alcl3 Alcl3-induced hepatorenal injury showed a highly significant elevation ( p < 0.05) by 250%, 200%, and 215% in the values of AST, ALT, and ALP, respectively, as compared with normal control group.

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