Brain MRI detects early-stage alterations and disease progression in Friedreich ataxia.

Brain Commun · 2023 · PMC10360047 · PMID 37483529

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a decreasing trendno p-value reported

an increasing trendno p-value reported

For example, for the total cerebellar volume, nearly all ‘Trio-Prisma’ pairs showed an increasing trend while most ‘same scanner’ pairs of data points (Trio-Trio or Prisma-Prisma) showed a decreasing trend ( Supplementary Fig. 1 ).

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highly significantno p-value reported

This is further supported by relatively strong (>0.5) and highly significant correlations between clinical metrics and C2–C3 spinal cord area and FDC of the SCP.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.