Heparanase 2 (Hpa2)- a new player essential for pancreatic acinar cell differentiation.

Quantification of the staining revealed a marked increase in oil red staining intensity in Hpa2-KO pancreas, exhibiting statistically highly significant differences between wt and Hpa2-KO pancreas (Fig. 1F , lower panel; 2.5 ± 0.7 vs 133.4 ± 23.3 for wt and Hpa2-KO pancreas, respectively; p < 0.0001).

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