Ten years of treatment with ruxolitinib for myelofibrosis: a review of safety.

Finally, in a noninterventional postauthorization safety study of 462 patients with MF that included prevalent or new users of ruxolitinib, a nonsignificant trend toward increased risk of NMSC with increasing ruxolitinib exposure was observed (hazard ratio [HR] corresponding to risk with each additional year of ruxolitinib, 1.2 [95% CI 0.9, 1.6]) [ 16 ].

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