Broad Sarbecovirus Neutralizing Antibodies Obtained by Computational Design and Synthetic Library Screening.

J Virol · 2023 · PMC10373554 · PMID 37367229

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an increasing trendno p-value reported

Interestingly, although the neutralization activity of AI-10 was significantly improved, the structural analysis did not find an increasing trend of polar interactions represented by hydrogen bonds ( Fig. 4C ), suggesting other enhancement mechanisms.

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