highly significantP = 0.000
In the full cohort of HCC patients, preoperative CTC ≥ 2 had marginally significant association with increased tumor number (P = 0.067) and higher Edmonson grade (P = 0.064), while it had highly significant association with increased tumor size (P = 0.000), presence of PVTT (P = 0.000), and consequently higher BCLC stage (P = 0.000).