Coupling the H295R with ERα and AR U2OS CALUX assays enables simultaneous testing for estrogenic, anti-androgenic and steroidogenic modalities.

Toxicol Sci · 2023 · PMC10375316 · PMID 37261848

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an increasing trendno p-value reported

Perfluorooctanesulfonic acid (PFOS) was the only chemical exhibiting an increasing trend for both endpoints, while not directly agonizing AR and ERα.

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