Alterations of gut microbiota are associated with brain structural changes in the spectrum of Alzheimer's disease: the SILCODE study in Hainan cohort.

Among them, Lachnospiraceae (LDA = 4.64), Lachnospiracea_incertae_sedis (LDA = 3.40), Fusicatenibacter (LDA = 3.29), and Anaerobutyricum (LDA = 2.69) had decreasing abundance with cognitive ability and a decreasing trend between groups; the abundance of family Rikenellaceae (LDA = 3.65) and Odoribacteraceae (LDA = 3.06), and genus Mediterraneibacter (LDA = 3.18) and Alistipes (LDA = 3.65) in individuals with SCD were significantly reduced compared with others and enriched in the CI group. 3.4.

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