Specific Blood Plasma Circulating miRs Are Associated with the Physiological Impact of Total Fish Meal Replacement with Soybean Meal in Diets for Rainbow Trout (<i>Oncorhynchus mykiss</i>).

However, no significant differences were found in the brush border integrity; degree of supranuclear vacuolization in enterocytes; enterocyte nuclei position; enterocyte height; height of villi; width of the submucosa, muscular, and serosa layers or goblet cell density, although the reduction in the goblet cell density in fish fed VM (from 29.36 ± 2.08 to 25.75 ± 2.19) was almost significant ( Figure 2 c,d; Student’s t -test: p = 0.054).

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