Challenges and Future Trends in Atopic Dermatitis.

Int J Mol Sci · 2023 · PMC10380015 · PMID 37511138

Europe PMC DOI

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failed to reach significanceno p-value reported

Although this molecule is a good biomarker, a study assessing the efficacy, safety, and pharmacokinetic profile of itepekimab (REGN3500), an anti-IL33 antibody ( Figure 2 b), administered subcutaneously to adult patients with moderate-to-severe AD failed to reach significance in a phase 2b clinical trial [ 51 ].

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highly significantno p-value reported

The IGA response in CBP201 was highly significant compared with placebo at week 16.

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