Porcine Circovirus 2 Increases the Frequency of Transforming Growth Factor-β via the C35, S36 and V39 Amino Acids of the ORF4.

In the IPEC-J2 transfected with ORF2, ORF4 or ORF5 plasmid, the expression of TGF-β mRNA was considerably upregulated at 24, 48 and 72 h with a decreasing trend over time ( Figure 1 C).

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