Relationship between Pharmacokinetic Profile and Clinical Efficacy Data of Three Different Forms of Locally Applied Flurbiprofen in the Mouth/Throat.

A comparison of AUC 0.25h and AUC 0.5h values for the different formulations revealed significant differences for granules and for lozenges when compared to the spray solution ( Table 3 ), although the AUC 0.5h comparison for lozenges with respect to the spray solution did not quite reach statistical significance.

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