For functional annotation of DEGs, GO enrichment analysis showed highly significant enrichment in the “myeloid leukocyte migration”, “leukocyte chemotaxis”, and “extracellular matrix” biological processes ( Figure 3B ); in the “collagen-containing extracellular matrix” and “endoplasmic reticulum lumen MHC protein complex” cellular components ( Figure 3C ); and in the “glycosaminoglycan binding”, “cytokine activity”, “receptor ligand activity”, and “signaling receptor activator activity” molecular functions ( Figure 3D ).
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A comprehensive analysis of biomarkers associated with synovitis and chondrocyte apoptosis in osteoarthritis.
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