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A pilot phase Ib study to evaluate tadalafil to overcome immunosuppression during chemoradiotherapy for IDH-wild-type glioblastoma.

Neurooncol Adv · 2023 · PMC10406429 · PMID 37554225

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a decreasing trendno p-value reported
Most tadalafil patients also showed a decreasing trend of the immunosuppressive regulatory T cells (Treg) at week 6 (11 out of 15 or 73%; Figure 2D ).

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