We observed an increasing trend line for the correlation coefficient between Stabilin-2 and a late endosome vesicle (Rab7) from 0- to 30-min chase (max), followed by a small decreasing trend line from 30- to 60-min chase leading to a constant trend line until it reached 120-min chase ( Figure 2 E).
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Chloroquine and cytosolic galectins affect endosomal escape of antisense oligonucleotides after Stabilin-mediated endocytosis.
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