Structure of gut microbiota and characteristics of fecal metabolites in patients with lung cancer.

Healthy controls had a significantly higher micro-biome functional profile, whereas the gut micro-biome of LC patients showed a decreasing trend in metabolic capacity during the disease.According to the screening criteria, we summarized that the top five metabolites with the best correlation to LC were quinic acid, 3-hydroxybenzoic acid, 1-methylhydantoin, 3,4-Dihydroxyhydrocinnamic acid and 3,4-Dihydroxybenzeneacetic acid ( Figure 5 ; Table S1 ).

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