Characteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling.

Front Endocrinol (Lausanne) · 2023 · PMC10415909 · PMID 37576955

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Significantly, there was a giant decrease in the level of total androgens in patients with SLE (P < 0.05), and there was a slight trend of elevation in total estrogens (P < 0.1, Figure 3 ). 3.5 Screening of altered steroid species in patients with SLE To reveal the specific alterations of steroids in patients with SLE, PLS-DA was conducted to compare the steroid profiles between two groups after OSC filtration.

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