Gut microbial beta-glucuronidase: a vital regulator in female estrogen metabolism.

It has been early noticed that the difference between the plasma β−glucuronidase enzyme levels of the women with and without gynecological cancers was highly significant and serial observations demonstrated a rising titer of β−glucuronidase as well as its enzyme activity were corresponding to deterioration process in clinical state. 58 , 59 Then, people found that some species of gut microbiota that produce gmGUS were abundant in breast cancer patients. 60 A recent

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