highly significantp = 3.17 10 −19
Interestingly, in the RPPA study of LUAD carcinomas, machine learning provided a highly significant signature of metastasis ( p = 3.17 10 −19 ) that included the expression of β-F1-ATPase, IF1, superoxide dismutase (SOD2), thioredoxin (TRX), peroxiredoxin 6 (PRX6) and 4-hydroxynonenal (4-HNE) modification of proteins [ 20 ].