Barely Significant
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PAI-1 Regulation of p53 Expression and Senescence in Type II Alveolar Epithelial Cells.

Cells · 2023 · PMC10417428 · PMID 37566086

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1
hedged sentence
0.0005
closest p · 0.0× alpha
0.0005
boldest claim

The sentences

highly significantp = 0.00046actually significant
We also found that the inhibition of PAI-1 activity with a small molecule PAI-1 inhibitor TM5275 almost completely restored the p53 protein degradation rate that was inhibited by bleomycin in A549 cells (the time-dependent changes in the amounts of p53 protein between bleomycin + TM5275 and bleomycin + solvent were highly significant, p = 0.00046; those between bleomycin + TM5275 and saline + TM5275 were not significant, p = 0.626; those between bleomycin +TM5275 and saline + solvent were not significant, p = 0.945) ( Figure 3 D,E).

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