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Differences in the pharmacokinetics and steady-state blood concentrations of orally administered lenvatinib in adult and juvenile rats.

Front Pharmacol · 2023 · PMC10420079 · PMID 37576809

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a decreasing trendno p-value reported
Additionally, the incidence and mortality rates of liver cancer in China have shown a decreasing trend in the past few decades, which may be attributed to the effective control of hepatitis B virus (HBV) infection and aflatoxin food contamination ( Torre et al., 2016 ; Benson et al., 2021 ).

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