Single-cell analysis reveals cellular reprogramming in advanced colon cancer following FOLFOX-bevacizumab treatment.

Front Oncol · 2023 · PMC10421721 · PMID 37576892

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an increasing trendno p-value reported

demonstrated an increasing trend of CTLA-4 expression in CRC tissues and cell lines, and treatment with capecitabine effectively suppressed the expression of CTLA-4 in CRC cells, suggesting a potential bridge between immunotherapy approaches and chemotherapy ( 40 ).

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