An investigation of neuromelanin distribution in substantia nigra and locus coeruleus in patients with Parkinson's disease using neuromelanin-sensitive MRI.

BMC Neurol · 2023 · PMC10424360 · PMID 37580712

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a decreasing trendno p-value reported

It was found that there were significant difference between groups and the CNR levels of each part of the SN and the LC decreased successively in healthy people, early patients, and progressive patients (p < 0.05), and the CNR level of the SNpc showed a decreasing trend from the ventral side to the dorsal side, see Table 2 ; Fig. 2 .

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