Changes in HIV-1 Subtypes/Sub-Subtypes, and Transmitted Drug Resistance Among ART-Naïve HIV-Infected Individuals - China, 2004-2022.

China CDC Wkly · 2023 · PMC10427497 · PMID 37593123

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a decreasing trendno p-value reported

Between 2004 and 2015, an increasing trend was noted in CRF01_AE, while subtypes B and C displayed a decreasing trend.

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an increasing trendno p-value reported

The Cochran-Armitage trend test results revealed an increasing trend over time in NNRTI resistance mutations for A98, E138, G190, K101, K103, K238, P225, V106 and V179, as well as in NRTI resistance mutations for L74 and M184 (all P <0.05 for trend).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.