Barely Significant
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Effects of sacubitril/valsartan on exercise capacity: a prognostic improvement that starts during uptitration.

Eur J Clin Pharmacol · 2023 · PMC10427709 · PMID 37368004

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a positive trendno p-value reported
3 ), showing how the observed favorable effects are independent from loop diuretic administration and actually allow a diuretic dose reduction which is considered a positive trend due to the diuretic drawbacks.

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almost significantno p-value reported
We recorded an almost significant reduction in the prescription of loop diuretics during the whole study period (Fig. 3 B).

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