Titrating CD47 by mismatch CRISPR-interference reveals incomplete repression can eliminate IgG-opsonized tumors but limits induction of antitumor IgG.

PNAS Nexus · 2023 · PMC10427748 · PMID 37593202

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a possible trendno p-value reported

We did not attain statistical significance between no repression and intermediate repression, but the reported P -value of 0.134 seems to suggest a possible trend of gradually increasing macrophage numbers with deeper CD47 repression.

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